For more information on SDS and specification sheets, see the attached documents on our website.
GelMA is derived from porcine gelatin and enhanced through the incorporation of methacrylate groups to improve printability. It also facilitates crosslinking to increase construct longevity. Compared to non-modified gelatin, this gelatin methacrylate retains its shape at physiological temperature and conditions. Alginate is isolated from the cell walls of brown algae and is one of the most commonly used biomaterials. Alginate is a versatile biomaterial that has been utilized in diverse applications ranging from food to drug delivery. Alginates consist of arrangements of (1-4)-linked-D-mannuronic acid (M units) and -Lguluronic acid (G units) monomers. Alginate’s biocompatibility, ease of use, and customizability has resulted in wide applications including bone and cartilage engineering, along with cell and drug delivery techniques.
The GelMA-Alginate Kit is sterile lyophilized powder that you dissolve at your target concentration to prepare as a bioink or 3D cell culture biomaterial.
The GelMA-Alginate Kit consists of sterile GelMA powder and Alginate powder along with an addition of photoinitiator necessary to blend your own bioink composition. Easy to use and to get started making and customizing your own GelMA-Alginate based bioinks or for use as a base material for 3D cell culture. The GelMA-Alginate bioink has been optimized for use with the BIO X system and temperature controlled printhead with thermal nozzle cover and the use of a cooled printbed. While the bioink can be used with the INKREDIBLE+ system due to its ability to heat the bioink, secondary steps are necessary to cool the printed structure to pre-gel it prior to crosslinking. Clogging may still occur due to lack of temperature control at the nozzle. Therefore, it is not recommended to use the bioink with the INKREDIBLE system since the bioink will not perform as expected and resulting filament characteristics may be inconsistent.
See the attached document for the reconstitution protocol.