For more information on SDS and specification sheets, see the attached documents on our website.
CELLINK LAMININK 121 is designed for cells that require the laminin 121 isoform. Laminin is an extracellular matrix protein predominantly found in the basal lamina of many tissues. Laminin has a foundational cross-like structure. Laminin has three domains: alpha, beta and gamma. Fifteen laminin trimers exist; each combination has a different role and cellular compatibility. Laminin 121 has a chain conformation of alpha1beta2gamma1, and it plays a critical role in cell activity. Laminin 121 maintains the universal CELLINK bioink’s excellent printability and ease of crosslinking.
CELLINK LAMININK 121 is a great starting point for culturing many cell types. This laminin variation is mostly found in the placenta, skeletal muscles and kidney tissues. CELLINK LAMININK 121 is a suitable base material for culturing specific cell types, including hepatocytes. CELLINK LAMININK 121 can be used to induce neural differentiation and study epithelial development. Compared to other heterogenous matrices, laminin’s xenographic source allows better control over the matrix environment.
See attached document for the bioprinting protocol.